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Article

Distinct subsets of synovial fibroblasts control cartilage destruction in joint diseases.

Clinical and experimental rheumatology - 1 May 2024

Chen Hung-Wei, Huang Chi-Hsiang, Huang Chi-Ying F, Chang Chih-Hung, Liao Hsiu-Jung

Abstract excerpt

Inflammation-induced bone destruction is the main cause of progressive joint damage in rheumatoid arthritis (RA) and osteoarthritis (OA). In addition, depending on the tissue microenvironment stimulators, the synovium transforms into a hyperplastic invasive tissue. The synovium includes two specific subsets of fibroblasts surrounding the joints: lining and sublining synovial fibroblasts (SFs). These SFs grow and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37706287
DOI: 10.55563/clinexprheumatol/txl9rm

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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