AIRRscape: an interactive tool for exploring B-cell receptor repertoires and antibody responses

Abstract excerpt

The sequencing of antibody repertoires of B-cells at increasing coverage and depth has led to the identification of vast numbers of immunoglobulin heavy and light chains. However, the size and complexity of these Adaptive Immune Receptor Repertoire sequencing (AIRR-seq) datasets makes it difficult to perform exploratory analyses. To aid in data exploration, we have developed AIRRscape, an R Shiny-based interactive...

Topics

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• Genetic Variation
• High-Throughput Nucleotide Sequencing
• Immunogenetics
• Immunoglobulins
• Monoclonal and Polyclonal Antibodies Research
• Receptors, Antigen, T-Cell
• Software
• T-cell and B-cell Immunology

Identifiers and source

Literature Corpus work

3cf23916-070e-5e44-bae4-582bb29b75a5

DOI

10.1101/2022.03.24.485594