Article
ARResT/Interrogate: an interactive immunoprofiler for IG/TR NGS data.
Bioinformatics (Oxford, England) - 1 Feb 2017
Bystry Vojtech, Reigl Tomas, Krejci Adam, Demko Martin, Hanakova Barbora, Grioni Andrea, Knecht Henrik, Schlitt Max, Dreger Peter, Sellner Leopold, Herrmann Dietrich, Pingeon Marine, Boudjoghra Myriam, Rijntjes Jos, Pott Christiane, Langerak Anton W, Groenen Patricia J T A, Davi Frederic, Brüggemann Monika, Darzentas Nikos
Abstract excerpt
Motivation: The study of immunoglobulins and T cell receptors using next-generation sequencing has finally allowed exploring immune repertoires and responses in their immense variability and complexity. Unsurprisingly, their analysis and interpretation is a highly convoluted task. Results: We thus implemented ARResT/Interrogate, a web-based, interactive application. It can organize and filter large amounts of...
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