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Comparative Mortality Risk of Aripiprazole, Olanzapine, Quetiapine and Risperidone in Alzheimer’s Disease: A Real□World Cohort Study with Treatment Effect Heterogeneity Analysis

2025-11-15

Abstract excerpt

<h4>Background</h4> Second-generation antipsychotics (SGAs) are frequently used off-label to manage behavioral symptoms in Alzheimer’s disease (AD), despite ongoing concerns about their safety. Comparative evidence on mortality risk across specific SGAs remains limited. <h4>Objective</h4> To compare all-cause mortality among AD patients treated with commonly prescribed SGAs and to explore treatment effect hetero...

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Literature Corpus work
3cd331c7-60cb-5242-87a9-fb9a6eace7f0
DOI
10.1101/2025.11.13.25340096
Open publication

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Comparative Mortality Risk of Aripiprazole, Olanzapine, Quetiapine and Risperidone in Alzheimer’s Disease: A Real□World Cohort Study with Treatment Effect Heterogeneity AnalysisDOI 10.1101/2025.11.13.25340096
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