Article

High accuracy label-free classification of kinetic cell states from holographic cytometry

2017-04-14

Abstract excerpt

Digital holographic microscopy permits live and label-free visualization of adherent cells. Here we report the application of this approach for high accuracy kinetic quantitative cytometry. We identify twenty-six label-free optical and morphological features that are biologically independent. When used as a basis for machine learning, these features allow blind single cell classification with up to 95% accuracy. W...

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Literature Corpus work: 3cc89760-1fa4-5890-b340-074b5f227211
DOI: 10.1101/127449

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