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Article

Quantitative non-invasive cell characterisation and discrimination based on multispectral autofluorescence features.

Scientific reports - 31 Mar 2016

Gosnell Martin E, Anwer Ayad G, Mahbub Saabah B, Menon Perinchery Sandeep, Inglis David W, Adhikary Partho P, Jazayeri Jalal A, Cahill Michael A, Saad Sonia, Pollock Carol A, Sutton-McDowall Melanie L, Thompson Jeremy G, Goldys Ewa M

Abstract excerpt

Automated and unbiased methods of non-invasive cell monitoring able to deal with complex biological heterogeneity are fundamentally important for biology and medicine. Label-free cell imaging provides information about endogenous autofluorescent metabolites, enzymes and cofactors in cells. However extracting high content information from autofluorescence imaging has been hitherto impossible. Here, we...

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Identifiers

PMID: 27029742
DOI: 10.1038/srep23453
PMCID: PMC4814840

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Source receipt: pubmed, retrieved 7 Sept 2026.

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