Article
Deep-learning-assisted biophysical imaging cytometry at massive throughput delineates cell population heterogeneity.
Lab on a chip - 21 Oct 2020
Siu Dickson M D, Lee Kelvin C M, Lo Michelle C K, Stassen Shobana V, Wang Maolin, Zhang Iris Z Q, So Hayden K H, Chan Godfrey C F, Cheah Kathryn S E, Wong Kenneth K Y, Hsin Michael K Y, Ho James C M, Tsia Kevin K
Abstract excerpt
The association of the intrinsic optical and biophysical properties of cells to homeostasis and pathogenesis has long been acknowledged. Defining these label-free cellular features obviates the need for costly and time-consuming labelling protocols that perturb the living cells. However, wide-ranging applicability of such label-free cell-based assays requires sufficient throughput, statistical power and...
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