Article

PNMA2 forms non-enveloped virus-like capsids that trigger paraneoplastic neurological syndrome

2023-02-09

Abstract excerpt

The paraneoplastic Ma antigen ( PNMA ) genes are associated with cancer-induced paraneoplastic syndromes that present with neurological symptoms and autoantibody production. How PNMA proteins trigger a severe autoimmune disease is unclear. PNMA genes are predominately expressed in the central nervous system with little known functions but are ectopically expressed in some tumors. Here, we show that PNMA2 is de...

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Literature Corpus work: 3c90f0ef-35c9-5756-8f85-75bd0b9bad37
DOI: 10.1101/2023.02.09.527862

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