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Article

High-resolution epitope mapping of anti-Hu and anti-Yo autoimmunity by programmable phage display

1 Jan 2020

Abstract excerpt

Abstract Paraneoplastic neurological disorders are immune-mediated diseases understood to manifest as part of a misdirected anti-tumor immune response. Paraneoplastic neurological disorder-associated autoantibodies can assist with diagnosis and enhance our understanding of tumor-associated immune processes. We designed a comprehensive library of 49-amino-acid overlapping peptides spanning the entire human...

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PMID: 32954318
DOI: 10.1093/braincomms/fcaa059

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