Article

A Multi-Layered Proteogenomic Framework for Prioritization of Cell Surface Therapeutic Targets in Solid Tumors

2026-06-02

Abstract excerpt

<h4>Background: </h4> Identification of tumor-specific cell surface targets is a critical step in the development of precision oncology therapeutics, including radioligand and antibody-based approaches. However, existing strategies often rely on single-layer analyses and lack systematic integration of proteomic, genomic, and clinical metadata. <h4>Methods:</h4> We developed a multi-layered proteogenomic filtering...

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Literature Corpus work: 3c771914-0d6d-54b4-b2d2-2655a75642a2
DOI: 10.20944/preprints202606.0178.v1

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