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Transcriptomic profiling and bioinformatics-driven statistical prioritization of CRC biomarkers: A step toward precision oncology

24 May 2025

Abstract excerpt

BACKGROUND: Colorectal adenocarcinoma (COAD) is among the most common causes of cancer-related death globally. Early detection and targeted therapy depend on identifying key molecular biomarkers that drive tumor progression. The molecular heterogeneity of COAD demands robust computational strategies to improve the accuracy of biomarker discovery. METHODS: We developed and implemented a comprehensive, multi-step...

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PMID: 40419032
DOI: 10.1016/j.gene.2025.149594

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