Article

Somatic mutations and genome stability maintenance in clonal coral colonies

2019-10-10

Abstract excerpt

One challenge for multicellular organisms is maintaining genome stability in the face of mutagens across long life spans. Imperfect genome maintenance leads to mutation accumulation in somatic cells, which is associated with tumors and senescence in vertebrates. Colonial reef-building corals are often large, can live for hundreds of years, rarely develop recognizable tumors, and are thought to convert somatic cell...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 3c37d0d0-f743-5900-a1fd-d1c564462ace
DOI: 10.1101/799643

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Somatic mutations and genome stability maintenance in clonal coral coloniesDOI 10.1101/799643Read

Somatic Mutations and Genome Stability Maintenance in Clonal Coral Colonies.Semantic proximity Read

Mosaic accumulation of somatic genetic variation and estimates of age in the long-lived reef-building coral <i>Acropora palmata</i>Semantic proximity Read

Comparative somatic genomics reveals divergent development of cell lineages across scleractinian coralsSemantic proximity Read

Mutations in coral soma and sperm imply lifelong stem cell renewal and cell lineage selectionSemantic proximity Read

Mutations in coral soma and sperm imply lifelong stem cell renewal and cell lineage selection.Semantic proximity Read

Somatic and germline mutational processes across the tree of lifeSemantic proximity Read

Genome instability: a conserved mechanism of ageing?Semantic proximity Read

Somatic mutation rates scale with lifespan across mammalsSemantic proximity Read

Prolonged persistence of mutagenic DNA lesions in somatic cells.Semantic proximity Read

Somatic and germline mutational processes across the tree of lifeSemantic proximity Read

Somatic mutation rates scale with lifespan across mammals.Semantic proximity Read

Genome sequencing of normal cells reveals developmental lineages and mutational processes.Semantic proximity Read