Article

Modeling mutational effects on biochemical phenotypes using convolutional neural networks: application to SARS-CoV-2

2021-01-28

Abstract excerpt

<h4>ABSTRACT</h4> Biochemical phenotypes are major indexes for protein structure and function characterization. They are determined, at least in part, by the intrinsic physicochemical properties of amino acids and may be reflected in the protein three-dimensional structure. Modeling mutational effects on biochemical phenotypes is a critical step for understanding protein function and disease mechanism as well as...

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Literature Corpus work: 5c5d8fcc-5d65-55f4-96d0-0970189e0a04
DOI: 10.1101/2021.01.28.428521

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