Article

Transcriptional repression by ApiAP2 factors is central to chronic toxoplasmosis

2017-01-15

Abstract excerpt

Bradyzoite differentiation is marked by major changes in gene expression resulting in a parasite that expresses a new repertoire of surface antigens hidden inside a modified parasitophorous vacuole called the tissue cyst. The factors that control this important life cycle transition are not well understood. Here we describe an important Toxoplasma transcriptional repressor mechanism controlling bradyzoite differe...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 3c2c19f2-1476-5a9d-a78c-cf3d6c2b511b
DOI: 10.1101/100628

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Transcriptional repression by ApiAP2 factors is central to chronic toxoplasmosisDOI 10.1101/100628Read

Opposing transcriptional mechanisms regulate <i>Toxoplasma</i> developmentSemantic proximity Read

<i>Toxoplasma gondii</i> AP2IX-4 regulates gene expression during bradyzoite developmentSemantic proximity Read

Toxoplasma gondii AP2IX-4 Regulates Gene Expression during Bradyzoite Development.Semantic proximity Read

<i>Toxoplasma gondii</i> AP2XII-2 contributes to proper progression through S-phase of the cell cycleSemantic proximity Read

Toxoplasmadevelopment - turn the switch on or off?Semantic proximity Read

AP2XII-1 is a negative regulator of merogony and presexual commitment in Toxoplasma gondiiSemantic proximity Read

The T oxoplasma nuclear factor TgAP2XI ‐4 controls bradyzoite gene expression and cyst formationSemantic proximity Read

Toxoplasma gondii AP2XII-2 Contributes to Proper Progression through S-Phase of the Cell CycleSemantic proximity Read

Constitutive upregulation of transcription factors underlies permissive bradyzoite differentiation in a natural isolate of <i>Toxoplasma gondii</i>Semantic proximity Read

The Epigenome, Cell Cycle, and Development in <i>Toxoplasma</i>Semantic proximity Read

<i>In vitro</i> production of cat-restricted <i>Toxoplasma</i> pre-sexual stages by epigenetic reprogrammingSemantic proximity Read

GCN5a is a telomeric lysine acetyltransferase whose loss primes <i>Toxoplasma gondii</i> for latencySemantic proximity Read