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Article

Toxoplasma gondii AP2IX-4 Regulates Gene Expression during Bradyzoite Development.

1 Jan 2017

Abstract excerpt

is a single-celled parasite that persists in its host as a transmissible tissue cyst. How the parasite converts from its replicative form to the bradyzoites housed in tissue cysts is not well understood, but the process clearly involves changes in gene expression. Here we report that parasites lacking a cell cycle-regulated transcription factor called AP2IX-4 display reduced frequencies of tissue cyst formation...

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PMID: 28317026
DOI: 10.1128/msphere.00054-17

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