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The T oxoplasma nuclear factor TgAP2XI ‐4 controls bradyzoite gene expression and cyst formation

14 Dec 2012

Abstract excerpt

Toxoplasma gondii undergoes many phenotypic changes during its life cycle. The recent identification of AP2 transcription factors in T. gondii has provided a platform for studying the mechanisms controlling gene expression. In the present study, we report that a recombinant protein encompassing the TgAP2XI-4 AP2 domain was able to specifically bind to a DNA motif using gel retardation assays. TgAP2XI-4 protein is...

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PMID: 23240624
DOI: 10.1111/mmi.12121

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