Article

Opposing transcriptional mechanisms regulate <i>Toxoplasma</i> development

2016-12-16

Abstract excerpt

<h4>ABSTRACT</h4> The Toxoplasma biology that underlies human chronic infection is developmental conversion of the acute tachyzoite stage into the latent bradyzoite stage. We investigated the role of two alkaline-stress induced ApiAP2 transcription factors, AP2IV-3 and AP2IX-9, in bradyzoite development. These factors were expressed in two overlapping waves during bradyzoite development with AP2IX-9 increasing e...

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Literature Corpus work: c83837cd-ed43-5e4b-97f1-74d5fb98212b
DOI: 10.1101/094847

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