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Article

AP2XII-1 is a negative regulator of merogony and presexual commitment in Toxoplasma gondii

26 Sept 2023

Abstract excerpt

ABSTRACT A transition from the asexual to sexual development in the widespread intracellular pathogen Toxoplasma gondii requires stage switching in its feline (definitive) host, but the mechanisms governing this process remain elusive. Here, we demonstrate a novel apicomplexan-specific transcription factor, Tg AP2XII-1, that controls the transition of the acutely infectious tachyzoite stage to a presexual...

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PMID: 37750704
DOI: 10.1128/mbio.01785-23

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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