Article

SIRT1 Expression and BRAF V600E Mutation in Papillary Thyroid Cancer: Implications for Diagnosis and Prognosis

2020-05-13

Abstract excerpt

<title>Abstract</title> <p>Background The BRAF V600E mutation is closely associated with aggressive clinicopathologic features and increased recurrence and disease-specific mortality of papillary thyroid cancer (PTC). Silent mating type information regulation 2 homolog-1 (SIRT1) has long been suggested to have tumor promotor activity and is strongly associated with the presence of BRAF mutations and higher grade...

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Literature Corpus work: 3beb87e8-45f7-57d5-abc6-6ed7d6da313f
DOI: 10.21203/rs.3.rs-27747/v1

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