Article

Hydropathicity-Based Prediction of Pain-Causing NaV1.7 Variants

2021-01-07

Abstract excerpt

<h4>Background: </h4> Mutation-induced variations in the functional architecture of the NaV1.7 channel protein are causally related to a broad spectrum of human pain disorders. Predicting in silico the phenotype of NaV1.7 variant is of major clinical importance; it can aid in reducing costs of in vitro pathophysiological characterization of NaV1.7 variants, as well as, in the design of drug agents for counteractin...

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Literature Corpus work: 3bc205c4-d2a4-5775-bc16-c71773acc5f5
DOI: 10.21203/rs.3.rs-131515/v1

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