Article

Interactions of curcumin’s degradation products with the A <i>β</i> <sub>42</sub> dimer: A computational study

2022-08-05

Abstract excerpt

<h4>ABSTRACT</h4> Amyloid- β (A β ) dimers are the smallest toxic species along the amyloid aggregation pathway and among the most-populated oligomeric accumulations present in the brain affected by Alzheimer’s disease (AD). A proposed therapeutic strategy to avoid the aggregation of A β into higher order structures is to develop molecules that inhibit the early stages of aggregation, i . e . dimerization. U...

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Literature Corpus work: 3b92d08f-fb93-5fbe-b6ee-4341bd62d93a
DOI: 10.1101/2022.08.03.502645

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