Article

Clonal analysis reveals differential PGC contributions to the early germline and ovarian reserve

2025-05-07

Abstract excerpt

Primordial germ cells (PGCs) are the precursors of the germline and among the first cells to be specified during embryogenesis. Contrary to the common assumption that PGCs directly develop into germline stem cells (GSCs), recent mammalian data and our zebrafish observations suggest a more complex picture. We hypothesized that individual PGCs contribute differentially to gonad development. To test this hypothesis,...

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Literature Corpus work: 3b89c469-21a5-5519-83d6-8ceaeea8af67
DOI: 10.1101/2025.04.30.651497

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