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Tracing and Characterizing the Development of Transplanted Female Germline Stem Cells In Vivo

18 May 2017

Abstract excerpt

It has long been believed that most female mammalian species lose the ability to generate oocytes in postnatal ovaries. Recent evidence has demonstrated the isolation and culture of female germline stem cells (FGSCs) from adult mice and humans. However, the process and mechanisms of FGSC differentiation in vivo following transplantation have not yet been studied. Here, we isolated and characterized FGSCs from a...

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PMID: 28528817
DOI: 10.1016/j.ymthe.2017.04.019

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