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Article

Behavioral characterization of mouse models of neuroferritinopathy.

PloS one - 1 Jan 2015

Capoccia Sara, Maccarinelli Federica, Buffoli Barbara, Rodella Luigi F, Cremona Ottavio, Arosio Paolo, Cirulli Francesca

Abstract excerpt

Ferritin is the main intracellular protein of iron storage with a central role in the regulation of iron metabolism and detoxification. Nucleotide insertions in the last exon of the ferritin light chain cause a neurodegenerative disease known as Neuroferritinopathy, characterized by iron deposition in the brain, particularly in the cerebellum, basal ganglia and motor cortex. The disease progresses relentlessly,...

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Identifiers

PMID: 25689865
DOI: 10.1371/journal.pone.0118990
PMCID: PMC4331086

Genes

FTL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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