Article

UCHL1 promotes lung cancer progression by stabilizing YAP1 and reprogramming ceramide metabolism

2026-06-25

Abstract excerpt

<title>Abstract</title> <p>Lung cancer remains a leading cause of cancer-related mortality worldwide, yet the molecular mechanisms driving its progression remain incompletely understood. Here, analysis of the GSE31210 dataset identified UCHL1 as a markedly upregulated deubiquitinase in lung cancer. Its high expression was validated in TCGA cohorts, clinical tissues, and lung cancer cell lines, and was associated...

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Literature Corpus work: 3b4b2730-80b3-54a5-bc77-d2f5099b16d3
DOI: 10.21203/rs.3.rs-10022995/v1

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