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Article

Neuroinvasive flavivirus pathogenesis is restricted by host genetic factors in Collaborative Cross mice, independently of Oas1b

2022-10-25

Abstract excerpt

<h4>ABSTRACT</h4> Powassan virus (POWV) is an emerging tick-borne flavivirus that causes neuroinvasive disease, including encephalitis, meningitis, and paralysis. Similar to other neuroinvasive flaviviruses, such as West Nile virus (WNV) and Japanese encephalitis virus (JEV), POWV disease presentation is heterogeneous, and the factors influencing disease outcome are not fully understood. We used Collaborative Cro...

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Literature Corpus work
3b3fe3d5-773a-58fe-9b24-1f40925c778b
DOI
10.1101/2022.10.24.513634
Open publication

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Neuroinvasive flavivirus pathogenesis is restricted by host genetic factors in Collaborative Cross mice, independently of Oas1bDOI 10.1101/2022.10.24.513634
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