Article

Investigation of Powassan virus lineage II pathogenesis and neurotropism in mice

2025-11-08

Abstract excerpt

Powassan virus (POWV) is an emerging tick-borne flavivirus that causes disease in humans. POWV has considerable genetic and phenotypic diversity, including highly variable replication in vitro and pathogenesis in mice. This study sought to define the extent of variability in pathogenesis within POWV lineage II in mice and investigate possible viral determinants. Relative to other strains, two New York-derived iso...

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Literature Corpus work: f306700f-50a0-5edd-825a-c7053267d582
DOI: 10.1101/2025.11.07.687151

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