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The power of TOPMed imputation for the discovery of Latino enriched rare variants associated with type 2 diabetes

2022-10-04

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Hypothesis</h4> The prevalence of type 2 diabetes is higher in Latino populations compared with other major ancestry groups. Not only has the Latino population been systematically underrepresented in large-scale genetic analyses, but previous studies relied on the imputation of ungenotyped variants based on the 1000 Genomes (1000G) imputation reference panel, which results in suboptimal captu...

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Literature Corpus work
3b2f75a8-31e9-57e5-af14-c2365c30b3c5
DOI
10.1101/2022.09.30.22280535
Open publication

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The power of TOPMed imputation for the discovery of Latino enriched rare variants associated with type 2 diabetesDOI 10.1101/2022.09.30.22280535
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