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Beyond Arrays: Leveraging Whole Genome Sequencing to provide insights into Type 1 Diabetes risk in the population

2024-06-13

Abstract excerpt

<title>Abstract</title> <p>A Type 1 Diabetes Genetic Risk Score (T1DGRS) aids diagnosis and prediction of Type 1 Diabetes (T1D). While traditionally derived from imputed array genotypes, Whole Genome Sequencing (WGS) provides a more direct approach and is used increasingly in research studies. We aim to assess differences between WGS-based T1DGRS and array-based T1DGRS, focusing on variations across genetic ances...

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Literature Corpus work: 17a16438-9873-5f48-a0e5-e6afcf389ed8
DOI: 10.21203/rs.3.rs-4466191/v1

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