Article

Single cell sequencing identifies serine proteases as regulators of myofibroblast differentiation

2020-08-20

Abstract excerpt

<title>Abstract</title> <p>Despite recent advances in understanding skin scarring, mechanisms triggering hypertrophic scar formation are still poorly understood. In the present study we performed single-cell sequencing of mature human hypertrophic scars and developing scars in mice. Compared to normal skin, we found significant differences in gene expression in most cell types present in scar tissue. Fibroblasts...

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Literature Corpus work: 3b176982-9078-5c7e-a9e2-b530b88f4b91
DOI: 10.21203/rs.3.rs-55007/v1

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