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Musashi-1 regulates cell cycle and confers resistance to cisplatin treatment in Group 3/4 medulloblastomas cells

2023-06-16

Abstract excerpt

<title>Abstract</title> <p>Groups (Grp) 3 and 4 are aggressive molecular subgroups of medulloblastoma (MB), with high rates of leptomeningeal dissemination. To date, there is still a paucity of biomarkers for these subtypes of MBs. In this study, we investigated the clinical significance and biological functions of Musashi-1 (<italic>MSI1)</italic> in Grp3 and Grp4-MBs. First, we assessed the expression profile o...

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Identifiers and source

Literature Corpus work
3aff5547-3d44-5741-8cc8-3df0d7f77c6a
DOI
10.21203/rs.3.rs-3026665/v1
Open publication

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