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Article

The RNA-Binding Protein Musashi1 Regulates a Network of Cell Cycle Genes in Group 4 Medulloblastoma.

Cells - 25 Dec 2021

Baroni Mirella, Guardia Gabriela D A, Lei Xiufen, Kosti Adam, Qiao Mei, Landry Tesha, Mau Karl, Galante Pedro A F, Penalva Luiz O F

Abstract excerpt

Medulloblastoma is the most common malignant brain tumor in children. Treatment with surgery, irradiation, and chemotherapy has improved survival in recent years, but patients are frequently left with devastating neurocognitive and other sequelae. Patients in molecular subgroups 3 and 4 still experience a high mortality rate. To identify new pathways contributing to medulloblastoma development and create new...

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Identifiers

PMID: 35011618
DOI: 10.3390/cells11010056
PMCID: PMC8750343

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