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Phytocarbon Nanodots Restore Glutathione Homeostasis via γ-Glutamylcysteine Synthetase against Ferroptosis-Driven Renal Fibrosis

2025-09-24

Abstract excerpt

Renal fibrosis remains a critical and refractory clinical condition, characterized by a dire lack of safe and effective pharmacological interventions. Its progression is propelled by dysregulated ferroptosis, an iron-dependent cell death pathway that drives pathological extracellular matrix deposition. To bridge this translational gap, we engineered a novel class of intrinsic nanotherapeutics through the atomic-le...

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Literature Corpus work: 3aff22b7-a62a-559c-94bd-f9c0cce97382
DOI: 10.22541/au.175874423.33548868/v1

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