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Hypoxia-Responsive Nanoreactors to Amplify Oxidative Damage Through Multiple Cascaded Pathways for Promoting Photodynamic/Ferroptosis-Induced ROS Generation and Simultaneously Disrupting Tumor Antioxidant Defense System

2021-05-18

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Photodynamic therapy (PDT), a typical reactive oxygen species (ROS)-dependent treatment with high controllability, has emerged as an alternative cancer therapy modality but its therapeutic efficacy is still unsatisfactory due to the limited light penetration and constant oxygen consumption. With the development of another ROS-dependent paradigm ferroptosis, seve...

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Literature Corpus work: 29f3d145-5f8e-5d7b-aa68-45b4de19fa81
DOI: 10.21203/rs.3.rs-523891/v1

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Hypoxia-Responsive Nanoreactors to Amplify Oxidative Damage Through Multiple Cascaded Pathways for Promoting Photodynamic/Ferroptosis-Induced ROS Generation and Simultaneously Disrupting Tumor Antioxidant Defense SystemDOI 10.21203/rs.3.rs-523891/v1Read

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