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Assembly of Genetically Engineered Ionizable Protein Nanocage-based Nanozymes for Intracellular Superoxide Scavenging

2024-04-30

Abstract excerpt

<title>Abstract</title> <p>Nanozymes play a pivotal role in mitigating excessive oxidative stress, however, determining their specific enzyme-mimicking activities for intracellular free radical scavenging is challenging due to endo-lysosomal entrapment. In this study, we employed a genetic engineering strategy to generate ionizable ferritin nanocages (iFTn), enabling their escape from endo-lysosomes and entry int...

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Literature Corpus work: 2d4322e3-c85b-5353-9c86-8a9c8f46414b
DOI: 10.21203/rs.3.rs-3880359/v1

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