Article

Antxr2-mediated fine-tuning of Collagen VI ensures skeletal muscle function

2025-09-19

Abstract excerpt

<h4>ABSTRACT</h4> Tissue function relies on the extracellular matrix (ECM) that surrounds cells, providing structural and biochemical support. The complex ECM composition depends on an adequately tuned balance between the deposition and degradation of each of its components. Disequilibrium may cause disease, as observed for Collagen VI (COL6), for which mutations lead to muscular dystrophy. Here, we investigated...

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Literature Corpus work: 3adc096a-9de9-538a-aa74-7568689fc825
DOI: 10.1101/2025.09.11.675515

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