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Article

An integrated strain-level analytic pipeline utilizing longitudinal metagenomic data.

Microbiology spectrum - 5 Nov 2024

Zhou Boyan, Wang Chan, Putzel Gregory, Hu Jiyuan, Liu Menghan, Wu Fen, Chen Yu, Pironti Alejandro, Li Huilin

Abstract excerpt

With the development of sequencing technology and analytic tools, studying within-species variations enhances the understanding of microbial biological processes. Nevertheless, most existing methods designed for strain-level analysis lack the capability to concurrently assess both strain proportions and genome-wide single nucleotide variants (SNVs) across longitudinal metagenomic samples. In this study, we...

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Identifiers

PMID: 39311770
DOI: 10.1128/spectrum.01431-24
PMCID: PMC11542597

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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