Article
VesicleVoyager: In vivo selection of surface displayed proteins that direct extracellular vesicles to tissue-specific targets
2025-06-07
Abstract excerpt
The development of technologies for screening proteins that bind to specific tissues in vivo and facilitate delivery of large cargos remains challenging, with most approaches limited to cell culture systems that often yield clinically irrelevant hits. To overcome this limitation, we developed a novel molecular screening platform using an extracellular vesicle (EV) display library. EVs are natural molecular carrier...
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Identifiers and source
- Literature Corpus work
- 3ad07124-0514-528b-8378-f54500eb130d
- DOI
- 10.1101/2025.06.04.657858