Article

A Mutant Methionyl-tRNA Synthetase-Based toolkit to assess induced-Mesenchymal Stromal Cell secretome in mixed-culture disease models

2023-05-03

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold> Mesenchymal stromal cells (MSCs) have a dynamic secretome that plays a critical role in tissue repair and regeneration. However, studying the MSC secretome in mixed-culture disease models remains challenging. This study aimed to develop a mutant methionyl-tRNA synthetase-based toolkit (MetRS<sup>L274G</sup>) to selectively profile secreted proteins from MSCs in m...

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Literature Corpus work: 3ab10114-c558-501d-8e2d-85c2d67bc3af
DOI: 10.21203/rs.3.rs-2838195/v1

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