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Comprehensive transcriptomic and proteomic characterization of human mesenchymal stem cells reveals source specific cellular markers

9 Feb 2016

Abstract excerpt

Mesenchymal stem cells (MSC) are multipotent cells with great potential in therapy, reflected by more than 500 MSC-based clinical trials registered with the NIH. MSC are derived from multiple tissues but require invasive harvesting and imply donor-to-donor variability. Embryonic stem cell-derived MSC (ESC-MSC) may provide an alternative, but how similar they are to ex vivo MSC is unknown. Here we performed an in...

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PMID: 26857143
DOI: 10.1038/srep21507

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