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Multiomics characterization of mesenchymal stromal cells cultured in monolayer and as aggregates

26 Feb 2020

Abstract excerpt

Mesenchymal stromal cells (MSCs) have failed to consistently demonstrate their therapeutic efficacy in clinical trials, due in part to variability in culture conditions used for their production. Of various culture conditions used for MSC production, aggregate culture has been shown to improve secretory capacity (a putative mechanism of action in vivo) compared with standard monolayer culture. The purpose of this...

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PMID: 32100872
DOI: 10.1002/bit.27317

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