Genetic variants of TNFSF4 and risk for carotid artery disease and stroke.

doi:10.1007/s00109-008-0412-5

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Article

Genetic variants of TNFSF4 and risk for carotid artery disease and stroke.

Journal of molecular medicine (Berlin, Germany) - 1 Apr 2009

Olofsson P S, Söderström L A, Jern C, Sirsjö A, Ria M, Sundler E, de Faire U, Wiklund P G, Ohrvik J, Hedin U, Paulsson-Berne G, Hamsten A, Eriksson P, Hansson G K

Abstract excerpt

In two independent human cohorts, the minor allele of SNP rs3850641 in TNFSF4 was significantly more frequent in individuals with myocardial infarction than in controls. In mice, Tnfsf4 expression is associated with increased atherosclerosis. The expression of TNFSF4 in human atherosclerosis and the association between genotype and cerebrovascular disease have not yet been investigated. TNFSF4 messenger RNA...

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Identifiers

PMID: 18998106
DOI: 10.1007/s00109-008-0412-5

Genes

TNFSF4
TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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