Article

CSF1R-CAR T cells induce CSF1R signalling and promote cancer cell growth

2024-12-20

Abstract excerpt

Chimeric antigen receptor (CAR) T cells have transformed the landscape of cancer therapy and demonstrate unprecedented success in treating relapsed/refractory blood cancers. The mechanism underlaying the interactions and responses of CAR T cells and their targets remain incompletely understood. Previous studies focus on the activation of CAR T cells and attempt to optimise CAR design to increase efficacy, meanwhil...

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Literature Corpus work: 3a0c8187-ece7-52b1-943b-41aedfeff1af
DOI: 10.1101/2024.12.17.629028

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