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Mitochondrial Energy Transformation Capacity Influences Brain Activation During Sensory, Affective, and Cognitive Tasks

2025-06-25

Abstract excerpt

Mitochondria supply the energy required for brain function, but how energetic capacity constrains human brain activity remains unclear. We compared patients with genetically defined mitochondrial disease to matched controls, testing whether bioenergetic stress selectively limits neural processes assessed with functional magnetic resonance imaging during rest and during tasks probing working memory, sensory percept...

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Literature Corpus work
39fb9bda-c605-5599-90b9-3d9873ff038f
DOI
10.1101/2025.06.25.661482
Open publication

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Mitochondrial Energy Transformation Capacity Influences Brain Activation During Sensory, Affective, and Cognitive TasksDOI 10.1101/2025.06.25.661482
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