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Individualised mapping of living human brain mitochondria by MRI reveals signatures of bioenergetic defects.

2026-07-22

Abstract excerpt

<title>Abstract</title> <p>Mitochondria power brain function and cognition, yet no label-free, non-invasive method has existed to explore their relationship to ageing, disease, and cognition in humans. The MitoBrainMap framework predicts mitochondrial features from magnetic resonance data alone, potentially bridging cellular biology with macroscale brain organization. Here we tested whether it captures meaningful...

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Literature Corpus work
41976367-639c-5374-aed0-dfd038129ac5
DOI
10.21203/rs.3.rs-10117408/v1
Open publication

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