Article

Calpain and Cardiometabolic Diseases

2023-10-17

Abstract excerpt

Calpain is delineated as a superfamily of cysteine proteases containing a CysPC motif within their genes. Among the fifteen species of mammalian homologs, calpain-1 and -2, which are categorized as conventional isozymes, execute limited proteolysis in a calcium-dependent fashion. Accordingly, the calpain system participates in physiological and pathological phenomena, encompassing cell migration, apoptosis, skelet...

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Literature Corpus work: 39fb662c-f93e-5397-b97d-e1583a4db5a5
DOI: 10.20944/preprints202310.0947.v1

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