Article
Calpain-related diseases.
Biochemical and biophysical research communications - 1 Oct 2004
Branca Donata
Abstract excerpt
Calpains are calcium-modulated proteases which respond to Ca2+ signals by removing limited portions of protein substrates, thereby irreversibly modifying their function(s). Members of this protease family are present in a variety of organisms ranging from mammals to plants; some of them are ubiquitously expressed, while others are tissue specific. Although calpains are apparently involved in a multitude of...
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