Article

Pulmonary Distribution and Lesion Penetration of Antimicrobials in Patients with Nontuberculous Mycobacterial Disease

2026-05-20

Abstract excerpt

<h4>Background</h4> The intrapulmonary pharmacokinetics of antimicrobial agents used to treat nontuberculous mycobacterial (NTM) pulmonary disease remain poorly characterized, limiting the optimization of dosing regimens. This study characterized the plasma and intrapulmonary pharmacokinetics of azithromycin, ethambutol, rifampicin, clofazimine, and amikacin, as well as their penetration into pulmonary lesion sit...

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Literature Corpus work: 39b733c7-f6aa-51b8-8ed8-50cc3dc40ede
DOI: 10.64898/2026.05.12.26352725

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