Article
Time-kill kinetics of slowly growing mycobacteria common in pulmonary disease.
The Journal of antimicrobial chemotherapy - 1 Oct 2015
Ferro Beatriz E, van Ingen Jakko, Wattenberg Melanie, van Soolingen Dick, Mouton Johan W
Abstract excerpt
OBJECTIVES: This study aimed to provide basic pharmacodynamic information for key antibiotics used to treat Mycobacterium avium and Mycobacterium xenopi pulmonary disease. METHODS: M. avium subspecies hominissuis IWGMT49 and M. xenopi ATCC 19250 type strains were used; the MICs of clarithromycin, amikacin and moxifloxacin were determined by broth microdilution. Time-kill assays were performed, exposing bacteria...
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