Article

Adipocyte IL-22RA1 signaling promotes structural and functional remodeling of white adipose tissue following acute intestinal damage

2025-11-16

Abstract excerpt

Interleukin (IL)-22 has been shown to play an important role in intestinal host defense and ameliorating high-fat diet (HFD)-induced metabolic disorders primarily through signaling in intestinal epithelial cells. Adipocytes have emerged as key immune–metabolic regulators that influence intestinal inflammation in inflammatory bowel disease (IBD). However, the role of IL-22RA1 signaling in adipocytes has not been ex...

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Identifiers and source

Literature Corpus work: 39743771-4c6b-567d-b5be-f23d9bbf4523
DOI: 10.1101/2025.11.14.688505

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